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目的探讨妊娠期糖耐量减低(GIGT)患者的血糖变化特点,指导GIGT患者的孕期处理。方法选择2009年12月至2010年3月在我院分娩的糖耐量减低患者48例,收集其门诊75gOGTT结果、空腹血糖(FBG及餐后2h血糖监测结果、入院时随机血糖及糖化血红蛋白(GHb)结果,并进行分析。同时随机抽取同期非GDM和GIGT产妇40例对照分析新生儿体重及胎儿窘迫等情况。结果 GIGT患者OGTT0、1h、2h、3h四点血糖异常率分别是:0%、20.4%、34.6%和44.9%,以2h和3h点异常为主,占GDM诊断依据的80.6%。48例患者中孕期空腹及餐后2h监测血糖果者24例,监测率50%,空腹血糖平均值(4.02±0.76)mmol/L,餐后2h血糖平均值(6.26±1.53)mmol/L,入院随机血糖平均值(5.08±0.96)mmol/L,检测均未发现GIGT患者血糖监测值达糖尿病诊断标准。两组患者羊水过多、先兆子痫、胎儿窘迫、新生儿窒息、巨大胎儿发生率无统计学差异,新生儿体重也无统计学差异。结论未监测到GIGT患者在妊娠期间发展为妊娠期糖尿病。
Objective To investigate the characteristics of blood glucose in patients with impaired glucose tolerance (GIGT) during pregnancy and to guide the treatment of GIGT during pregnancy. Methods Forty-eight patients with impaired glucose tolerance who were delivered in our hospital from December 2009 to March 2010 were enrolled in the study. Results of 75 gOGTT, fasting blood glucose (FBG) and postprandial blood glucose monitoring (2h), random blood glucose and glycated hemoglobin ) Were analyzed.At the same time we randomly selected 40 pregnant women with non-GDM and GIGT during the same period to analyze the newborn’s body weight and fetal distress.Results The abnormal glucose levels of OGTT at 0, 1h, 2h and 3h were 0% 20.4%, 34.6% and 44.9% respectively, which were mainly anomalies at 2h and 3h, accounting for 80.6% of the diagnoses based on GDM.Among the 48 patients, 24 were monitored fasting and 2h postprandial blood glucose monitoring, with a monitoring rate of 50%, fasting blood glucose (4.02 ± 0.76) mmol / L, mean postprandial blood glucose at 2h (6.26 ± 1.53) mmol / L, and mean admission random blood glucose (5.08 ± 0.96) mmol / L. No blood glucose monitoring was found in GIGT patients There was no significant difference in the incidence of preterm eclampsia, fetal distress, neonatal asphyxia and macrosomia between the two groups, and there was no significant difference in body weight between the two groups.Conclusion The development of GIGT during pregnancy is not detected For gestational diabetes.