论文部分内容阅读
目的:综合分析运动锻炼对慢性心衰患者血浆N末端脑钠肽前体(NT-proBNP)浓度及左心室射血分数(LVEF)的影响,评价运动锻炼对慢性心衰患者的康复效果。方法:检索PubMed、HighWire、Google Scholar、中国知网等数据库1990-2011年的所有相关文献,查找符合纳入标准的随机对照试验进行质量评估,运用stata7.0统计软件对提取的相关数据进行Meta分析。结论:中等强度的运动锻炼可显著降低患者血浆NT-proBNP浓度,提高其LVEF值,改善慢性心衰患者的心功能。
OBJECTIVE: To analyze the effect of exercise on the plasma concentration of NT-proBNP and left ventricular ejection fraction (LVEF) in patients with chronic heart failure, and to evaluate the rehabilitation effect of exercise on patients with chronic heart failure. Methods: All the relevant databases of PubMed, HighWire, Google Scholar, CNKI and other databases from 1990 to 2011 were searched to find the quality of the randomized controlled trials that meet the inclusion criteria. Meta-analysis was performed on the extracted data using stata7.0 statistical software . Conclusion: Moderate-intensity exercise can significantly reduce the plasma concentration of NT-proBNP, increase its LVEF and improve the heart function in patients with chronic heart failure.