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网络药理学是药理学的一个分支，通过生物网络构建、网络分析和实验验证预期结果的方法研究药物-基因-靶点-疾病之间复杂的生物网络关系。网络药理学在研究复杂成分药物治疗复杂发病机制疾病中具有独特优势。网络药理学主要在新药研发、药物作用机制、中药及其复方研究、药物重定位和毒理学研究等领域中得到应用，在眼部疾病中主要涉及细菌性结膜炎、视网膜静脉阻塞、糖尿病视网膜病变和视网膜色素变性等疾病。网络药理学在眼科的应用前景主要体现在探寻中药治疗眼科疾病的有效物质、疾病靶点和通路，药物重定位和在眼科基础研究寻找下游靶点3个方面，我们需要加大网络药理学在眼科中的应用范围。本文对网络药理学的概念、研究方法、应用领域、在眼科的应用等研究进展进行综述。“,”Network pharmacology is a branch of pharmacology, and it primarily studies the complex biological network relationship among drugs, genes, targets and diseases through biological network construction, network analysis and experimental verification of expected results.Network pharmacology has its unique advantage in the study of drugs with complex component in treating diseases with complex pathogenesis and is mainly used in research and development of new drugs, disclosure of drug mechanism, studies of traditional Chinese medicine and its compound, drug reorientation and toxicology.The reasearch of network pharmacology in treating eye diseases mainly involves bacterial conjunctivitis, retinal vein occlusion, diabetic retinopathy, retinitis pigmentosa, etc.The application prospect of network pharmacology in ophthalmology is mainly in exploring the effective substances, disease targets and pathways of traditional Chinese medicine in the treatment of ophthalmic diseases, drug repositioning and finding downstream targets in ophthalmic basic research.The research progress of network pharmacology in ophthalmology was reviewed, including the concept, research methods and application fields.