大鼠肠粘膜匀浆含有一种能抑制脂质过氧化作用的物质,把它加入肝线粒体或微粒体体外培养物里,可阻止这些亚细胞组分诱生的过氧化作用,该物质可用甲醇萃取。经分析,缺乏维生素E的无菌大鼠、胎鼠或新生鼠的肠粘膜也含有该活性物质,表明不是α-生育酚,也非肠道菌丛产物。经薄层析提纯后发现,该活性物质系下列脂肪酸混合物:棕榈酸14.8％、棕 The rat intestinal mucosa homogenate contains a substance that inhibits lipid peroxidation, adding it to liver mitochondria or microsome cultures in vitro to prevent peroxidation induced by these subcellular components, which can be treated with methanol extraction. It has been analyzed that the intestinal mucosa of aseptic, vitamin E deficient, fetal or neonatal rats also contains the active substance, indicating that it is not an α-tocopherol, nor a product of the intestinal flora. After purification by thin-layer chromatography, it was found that the active substance is a mixture of the following fatty acids: palmitic acid 14.8%, brown