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目的观察紫龙金片对局部晚期非小细胞肺癌(NSCLC)患者生活质量(QOL)的影响。方法将78例局部晚期非小细胞肺癌经同步放化疗后病情稳定者随机分为治疗组和对照组(各39例),分别给予紫龙金片和安慰剂维持治疗,疗程2个月。观察两组治疗前后临床症状和生活质量评分变化情况。结果治疗后治疗组神疲乏力等症状积分较治疗前明显降低(P<0.05),且低于对照组(P<0.05);治疗组躯体功能等生活质量评分较治疗前改善(P<0.05),且治疗组改善优于对照组(P<0.05)。结论紫龙金片维持治疗能改善晚期非小细胞肺癌的临床症状,提高患者生活质量。
Objective To observe the effect of Zilongjin tablet on quality of life (QOL) in patients with locally advanced non-small cell lung cancer (NSCLC). Methods Seventy-eight patients with locally advanced non-small cell lung cancer (NSCLC) after stable chemoradiotherapy were randomly divided into treatment group (39 cases) and control group (39 cases), respectively. The changes of clinical symptoms and quality of life before and after treatment were observed. Results After treatment, the score of neuropsychiatric symptoms in treatment group was significantly lower than that before treatment (P <0.05), and lower than that in control group (P <0.05). The scores of physical function such as body function in treatment group were improved (P <0.05) , And the treatment group improved better than the control group (P <0.05). Conclusion The treatment of Zilongjin gold can improve the clinical symptoms of advanced non-small cell lung cancer and improve the quality of life of patients.