奇异变形杆菌(Proteus Mirabilis)和摩根变形杆菌(Proteus Morgani)相似,经常存在于人粪便中,常引起肠源性尿路感染。在普遍使用广谱抗生素后,变形杆菌已成为重要的条件致病菌,有时可引起严重感染,包括医源性感染,往往造成病人死亡。与奇异变形杆菌致病性相关的尿素酶在泌尿道感染中所起的作用,近来受到许多研究者的重视,进一步阐述了尿素酶与泌尿临床关系极为密切,现简述于下。 Proteus Mirabilis, similar to Proteus Morgani, is often found in human faeces and often causes gut urinary tract infections. Proteus has become an important opportunistic pathogen after the widespread use of broad-spectrum antibiotics and can sometimes cause serious infections, including iatrogenic infections, often resulting in the death of patients. The role of urease associated with pathogenicity of Proteus mirabilis in urinary tract infections has recently attracted the attention of many researchers and further elucidates the very close relationship between urease and urinary clinic.