前列腺素(PG)与女性生殖的关系极为密切,在生理方面,它几乎影响到女性生殖功能的各个方面,包括下丘脑——腺垂体促性腺激素的释放、排卵、黄体功能的调节、输卵管运动、月经、妊娠、分娩直至胎儿循环等;在病理生理方面,它与痛经、功能性子宫出血、提前分娩、先兆子痫以及早产儿动脉导管未闭等的发病密切相关。PG用于临床首先也是在妇产科领域。本文主要综述PG与某些妇产科疾病发病的关系。 PG与原发性痛经过去长时间对原发性痛经的病因了解很少,因此有效的治疗方法也很少。近年来大量研究资料证明,PG是引起原发性痛经的主要原因。其根据主要有:1.原发性痛经妇女子宫内膜、月经液及外周 Prostaglandin (PG) has a very close relationship with female reproduction and physiologically it affects almost all aspects of female reproductive function, including hypothalamic-pituitary gonadotropin release, ovulation, regulation of luteal function, tubal motility , Menstruation, pregnancy, childbirth until fetal circulation; in the pathophysiology, it is closely related to the incidence of dysmenorrhea, dysfunctional uterine bleeding, early delivery, preeclampsia and patent ductus arteriosus in preterm infants. PG is also used clinically first in the field of obstetrics and gynecology. This article mainly summarizes the relationship between PG and some obstetrics and gynecology diseases. PG and primary dysmenorrhea for a long time on the etiology of primary dysmenorrhea little understanding, so effective treatment is also very small. In recent years, a large number of research data show that PG is the main cause of primary dysmenorrhea. According to the main are: 1. Primary dysmenorrhea women’s endometrium, menstrual fluid and peripheral