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目的:分析儿童侵袭性纤维瘤的预后影响因素。方法:回顾性分析某肿瘤医院1980年1月-2005年12月收治的儿童侵袭性纤维瘤33例,对可能影响患儿局部复发的因素,包括年龄、性别,肿瘤的部位、大小,就诊之前是否曾经复发,切缘情况,是否行放疗等进行Log-Rank单因素及Cox比例风险分析。结果:影响肿瘤局部复发率的因素为切缘情况及复发史(P<0.05);性别、年龄、肿瘤大小、肿瘤位置及有无行放疗与复发率均无显著相关性(P>0.05)。对切缘情况及复发史再进行Cox比例风险分析,结果显示,两个因素均不是肿瘤复发的独立预后因素(P>0.05)。结论:切缘情况及治疗前是否曾经复发为影响预后的主要因素,应尽早行根治性切除。
Objective: To analyze the prognostic factors of childhood invasive fibroma. Methods: A retrospective analysis of 33 children with invasive fibroma in a tumor hospital from January 1980 to December 2005 retrospectively analyzed the factors that may affect the local recurrence in children, including age, gender, tumor location, size, Whether recurrence, margins, radiotherapy or not, Log-Rank single factor and Cox proportional hazards analysis. Results: The factors influencing the local recurrence rate were margins and recurrence (P <0.05). There was no significant correlation between gender, age, tumor size, tumor location and the presence or absence of radiotherapy and recurrence rate (P> 0.05). Cox proportional hazards analysis was performed on the margins and relapse history. The results showed that neither of the two factors was an independent prognostic factor for tumor recurrence (P> 0.05). Conclusion: The resection margin and the recurrence before treatment are the main factors influencing the prognosis. Radical resection should be carried out as soon as possible.