以邻氯苯胺和硫氰酸铵为原料,在水溶液中合成邻氯苯基硫脲,探讨了原料配比、反应温度、反应时间对收率的影响。得到最佳条件:邻氯苯胺与硫氰酸铵的配比1:1.05(Mol/Mol),邻氯苯胺与盐酸的配比1:1.1(Mol/Mol),反应温度80℃,反应时间16小时。在此工艺条件下,制得产品的纯度为93.9%,收率为90.0%。 With o-chloroaniline and ammonium thiocyanate as raw materials, o-chlorophenylthiourea was synthesized in aqueous solution. The effects of the ratio of raw materials, reaction temperature and reaction time on the yield were discussed. The optimal conditions were as follows: the molar ratio of o-chloroaniline to ammonium thiocyanate was 1: 1.05 (mol / mol); the ratio of o-chloroaniline to hydrochloric acid was 1: 1.1 (mol / mol); the reaction temperature was 80 ℃; the reaction time was 16 hour. Under the conditions of this process, the purity of the product obtained was 93.9% and the yield was 90.0%.