论文部分内容阅读
48例肺癌胞转移瘤放疗后总的症状缓解率为87.5%。全脑照射20一30Gy(A组)、31~406y(B组)以及31~406y+缩野补充照射20一30Gy(C组)的症状缓解率分别为90.0%、92.9%和97.6%,三组间差异无统计学意(X2=1.96p=0.3756)。A、B、C三组的症状完全缓解率分别为47.5%、78.6%和80.5%,A组与B组、A组与C组之间差异有统计学意义;B组与C组之间差异无统计学意义。建议对于全身情况差、估计生存期短的病人,全脑照射时采用较低剂量短疗程的放射治疗方案,如20一30Gy/1一2周或20一30Gy/2一3周;全身情况较好,无颅外远处转移的单个脑转移灶、宜用高剂量放射方案,对于不能手术的单个脑转移灶,尽可能局部追加照射至50~60Gy,能手术者,应尽早手术,术后常规全脑照射31一40Gy/3一4周。
48 cases of lung cancer metastases after radiotherapy, the overall symptom response rate was 87.5%. Symptom remission rates were 90.0%, 92.9% and 97% for whole brain irradiation at 20 to 30 Gy (group A), 31 to 406 y (group B), and 31 to 406 y + .6%, no significant difference between the three groups (X2 = 1.96p = 0.3756). The complete remission rate of group A, B and C was 47.5%, 78.6% and 80.5% respectively. There was significant difference between group A and group B, group A and group C. Group B There was no significant difference between C group and C group. Recommendations for patients with poor general condition, short survival expectancy, whole-brain irradiation with a lower dose of short-course radiotherapy programs, such as 20 to 30 Gy / 1 to 2 weeks or 20 to 30 Gy / 2 to 3 weeks; systemic conditions Good, no extracranial distant metastasis of a single brain metastasis, should use high-dose radiation program, for inoperable single brain metastases, as far as possible additional local irradiation to 50 ~ 60Gy, who can surgery, surgery should be as soon as possible after surgery Conventional whole brain irradiation 31 a 40Gy / 3 a 4 weeks.