胃粘膜对酸/胃蛋白酶的消化作用有特殊的抵抗能力,但其保护机制的性质不甚明了。按Code和Davenport的假说,对酸的屏障位于表层上皮细胞的顶端膜。但晚近研究提示,胃粘膜保护可能由含碳酸氢盐的胃粘液层、间质内碳酸氢盐、粘膜血流、粘膜损伤后的再生能力以及疏水的表层上皮这些机制共同完成。粘液:胃粘液层的糖蛋白基质能有效地防止胃蛋白酶及同样大小的分子通过。作者最近测定氢离子通过 Gastric mucosa has special resistance to the digestion of acid / pepsin, but the nature of its protective mechanism is not clear. According to the Code and Davenport hypothesis, the acid barrier is located on the apical membrane of the epidermal cells. However, recent studies suggest that gastric mucosal protection may be accomplished by mechanisms such as bicarbonate-containing gastric mucus layers, interstitial bicarbonate, mucosal blood flow, regenerative capacity after mucosal injury, and hydrophobic superficial epithelium. Mucus: The gastric mucus layer of the glycoprotein matrix can effectively prevent the pepsin and the same size of the molecule through. The authors recently determined the passage of hydrogen ions