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患者男,72岁,右侧臀部黑色斑片3年,快速增大伴破溃3月余。皮肤科情况:右侧臀部见一4cm×3cm大黑色斑块,界清,表面破溃结痂。皮损组织病理学检查:肿瘤位于真皮浅层,与表皮相连,由基底样细胞团块构成,周边细胞呈栅栏状排列,可见收缩间隙,肿瘤团块内及间质内见多数色素颗粒及噬色素细胞。肿瘤细胞CK5/6弥漫阳性,Ber-EP4局灶性阳性。诊断为浅表性色素性基底细胞癌。确诊后给予扩大手术切除治疗,目前患者在随访中。
Male patient, 72 years old, right hip black patches for 3 years, rapid increase with rupture more than 3 months. Dermatology: the right side of the buttocks see a 4cm × 3cm big black plaque, clear, ulcerated scab on the surface. Histopathological examination of the lesion: The tumor was located in the superficial layer of the dermis and connected with the epidermis. The cells were composed of basal-like cell masses. The surrounding cells were arranged in a palisade pattern. The contractile gap and the majority of the pigment granules and bilges in the tumor mass and the interstitium Pigment cells. The tumor cells CK5 / 6 diffuse positive, Ber-EP4 focal positive. Diagnosis of superficial pigmented basal cell carcinoma. After the diagnosis of extended surgical resection, the current patient at follow-up.