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合成用 N-去甲-N-乙基红霉素 A 在冰醋酸、室温下制备。药理作用 EM-523是一个有力的增强胃肠的胃动素活性的红霉素衍生物。它的效应已在离体的兔、鼠、豚鼠肠标本中研究。与胃动素和前列腺素 F_2α(PGF_2α)效应相
The synthesis was performed with N-nor-N-ethyl erythromycin A in glacial acetic acid at room temperature. Pharmacological Effects EM-523 is a potent erythromycin derivative that enhances gastrointestinal motilin activity. Its effect has been studied in isolated rabbit, mouse and guinea pig intestine specimens. And motilin and prostaglandin F_2α (PGF_2α) effect phase