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介绍Ｌ－乳酸脱氢酶可逆催化氧化Ｌ－乳酸生成丙酮酸的反应机理研究的最新进展。讨论底物及活性中心附近残基的构型对反应的影响以及Ｈ－ 离子转移的可能机理。
The recent progress in the research on the reaction mechanism of L-lactate dehydrogenase to catalyze the reversible catalytic oxidation of L-lactic acid to pyruvate is described. The effect of the configuration of the residues near the substrate and the active site on the reaction and the possible mechanism of H-ion transport were discussed.