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目的:比较脑络宁胶囊与西医常规疗法治疗急性脑卒中的效果。方法:脑络宁组(20例)每天口服脑络宁胶囊3次,每次3粒,疗程28天。常规治疗组脑血栓形成病例给予低分子右旋糖酐氨基酸250ml静脉滴注,每天1次,疗程28天。对两组中脑出血病例均实施脱水降颅压措施。结果:脑络宁组治疗后神经功能缺损下降值为9.4±1.8,常规治疗组为3.8±1.5,两组比较结果表明,脑络宁组积分下降幅度比常规治疗组大(P<0.01)。脑络宁组治疗后CT示梗塞灶面积缩小7.2±8.2cm~2,常规治疗组(5例)为6.4±5.0cm~2。脑络宁组治疗后脑出血量平均吸收11.7±4.8ml,常规治疗组(5例)为5.2±2.8ml。两组比较,脑络宁组治疗急性脑卒中的有效率为95％,常规治疗组为90％,前者疗效优于后者(P<0.01)。结论:脑络宁胶囊治疗急性脑卒中有明显疗效,值得在临床推广应用。
Objective: To compare the effect of Naoluoning capsule and conventional western medicine in the treatment of acute stroke. Method: Naoluoning group (n = 20) was given oral Naoluoning capsules three times a day for 3 days for 28 days. Routine treatment group of patients with cerebral thrombosis given low molecular weight dextran amino acid 250ml intravenous infusion, once daily for 28 days. On the two groups of patients with cerebral hemorrhage are dehydration reduce intracranial pressure measures. Results: The decrease of neurological deficit in Naoluoning group was 9.4 ± 1.8 after treatment, and 3.8 ± 1.5 in conventional treatment group. The comparison between the two groups showed that the decline of integral of Naoxuning group was larger than that of conventional treatment group (P <0.01). The results showed that the area of cerebral infarction lesion reduced by 7.2 ± 8.2cm ~ 2 after CTOL treatment and that of conventional treatment group (6.4 ± 5.0cm ~ 2). The amount of cerebral hemorrhage in Naoluoning group was 11.7 ± 4.8ml on average, and 5.2 ± 2.8ml in conventional treatment group (5 cases). Compared with the two groups, the effective rate of Naoxueling group in treating acute stroke was 95% and that in the conventional treatment group was 90%. The former was better than the latter in the latter (P <0.01). Conclusion: Naoluoning Capsule in the treatment of acute stroke has a significant effect, it is worth in the clinical application.