最近,一项刊登在国际杂志Nature上的研究报告中,来自耶鲁大学的研究人员通过研究揭示了如何通过控制血管发育来帮助开发治疗心血管疾病以及癌症的新型疗法。正常的血管生长会被诸如生长因子等蛋白质或激素所调节;在本文研究之前,研究人员并不清楚特殊的生长因子家族(FGFs)在调节血管生长发育过程中所扮演的角色,为了进行深入研究,研究者Michael Simons及其同事对工程化小鼠进行研究,他们对小鼠进行遗传工程化操作,使其血管内皮中缺少FGF信号。 In a recent study published in the international journal Nature, researchers from Yale University revealed through research how to help develop new treatments for cardiovascular disease and cancer by controlling blood vessel development. Normal blood vessel growth is regulated by proteins or hormones such as growth factors; before the present study, researchers were not aware of the role of specific growth factor families (FGFs) in regulating vascular growth and development. For further studies , Researcher Michael Simons and colleagues studied engineered mice that genetically engineered mice to lack FGF signaling in their vascular endothelium.