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目的探讨血清同型半胱氨酸(HCY)与冠心病的关系,观察盾叶冠心宁对HCY的影响。方法选取2014年11月-2015年12月医院内科收住院的家族中无同型半胱氨酸尿症患者82例。按患者病情分为冠心病组46例与对照组36例。冠心病组按治疗方法不同分为盾叶冠心宁组与叶酸、维生素B12组,治疗2周内观察血清HCY水平变化。结果盾叶冠心宁组HCY水平高于健康对照组,2组比较差异有显著性,叶酸、维生素B12及盾叶冠心宁治疗后受试者血HCY水平均下降,统计学比较差异有显著性。结论冠心病与血清HCY水平有一定关系,盾叶冠心宁可降低血清HCY水平,对治疗冠心病的治疗及改善预后具有较高的临床价值。
Objective To investigate the relationship between serum homocysteine (HCY) and coronary heart disease (CHD) and to observe the effect of Guanye Guanxinning on HCY. Methods Eighty-two patients with homocysteineuria in the hospital from November 2014 to December 2015 were selected. According to the patient’s condition was divided into coronary heart disease group 46 cases and control group 36 cases. Coronary heart disease group according to the different treatment methods are divided into the shield Ye Guan Ning group and folic acid, vitamin B12 group, the treatment of serum HCY levels were observed within 2 weeks. Results The HCY level in Duanye Guanxinning group was higher than that in healthy control group. There was significant difference between the two groups. The levels of HCY in blood serum of patients with folic acid, vitamin B12 and Guanye Guanning decreased after the treatment, and the difference was statistically significant. Conclusion Coronary heart disease and serum HCY levels have a certain relationship, shield Yexinxin can reduce serum HCY levels, the treatment of coronary heart disease and improve the prognosis of high clinical value.