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目的观察缬沙坦联合氨氯地平治疗社区老年高血压伴糖尿病的疗效。方法选取本院收治2014年2月至2016年2月社区老年高血压伴糖尿病患者80例,依不同的用药方式分成两组,对照组单纯采用缬沙坦治疗,治疗组联合采用氨氯地平治疗,比较两组的血糖、血压情况和不良反应。结果治疗组的空腹血糖、餐后2h血糖、收缩压、舒张压下降程度均优于对照组(P<0.05),而不良反应总发生率为12.54%,与对照组10.03%相差不大(P>0.05)。结论缬沙坦联合氨氯地平治疗社区老年高血压伴糖尿病,降压及降糖效果优于单用缬沙坦,且不增加患者的不良反应,具推广价值。
Objective To observe the efficacy of valsartan combined with amlodipine in the treatment of elderly patients with hypertension and diabetes mellitus. Methods Eighty elderly patients with hypertension and diabetes mellitus in our community were selected from February 2014 to February 2016 in our hospital. Patients in the control group were treated with valsartan alone and amlodipine combined with amlodipine , Comparing the two groups of blood sugar, blood pressure and adverse reactions. Results The fasting blood glucose, 2h postprandial blood glucose, systolic blood pressure and diastolic blood pressure were lower in the treatment group than those in the control group (P <0.05), while the total incidence of adverse reactions was 12.54%, which was not significantly different from that of the control group (P > 0.05). Conclusion Valsartan combined with amlodipine treatment of elderly patients with hypertension associated with diabetes, antihypertensive and hypoglycemic effect is better than valsartan alone, and does not increase the adverse reactions in patients with a promotional value.