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1977年Karp等报导了羊膜囊穿刺中发现羊水里含胎粪并无重要临床意义。此后相继的报导提出异议,认为胎粪污染羊水将有30%胎儿夭折的可能。作者自1978～1983年连续观察4709例妊娠中期遗传学羊膜囊穿刺的结果,以提供评价自发性流产的较可靠资料。本研究自1978～1983年在Oregan医科大学进行了2946例连续羊膜囊穿刺;1981～1983年在Emanuel医院围产中心进行了1763例羊膜囊穿刺。穿刺方法是:操作前先用超声波判定孕龄、胎盘定位和确定多胎或胎儿畸形,然后用22号腰椎穿刺针在超声波引导下进行穿刺,同时监护胎心变化。抽出的羊水用分光光度扫描仪分析羊水成
1977 Karp et al reported amniotic sac puncture found amniotic fluid containing meconium no significant clinical significance. Subsequent reports after objections, that meconium-contaminated amniotic fluid will have 30% of fetal deaths may be. From 1978 to 1983, the authors continuously observed the results of 4709 gestational metaphase amniocentesis in gestation to provide more reliable information for evaluating spontaneous abortion. In this study, 2,946 consecutive amniocentesis were performed at Oregan Medical University from 1978 to 1983; 1,763 amniocentesis were performed at perioperative center of Emanuel Hospital from 1981 to 1983. Puncture method is: before operation with ultrasound to determine gestational age, placenta positioning and to determine multiple births or fetal malformations, and then with the No. 22 lumbar puncture needle under ultrasound guidance puncture, while monitoring changes in fetal heart rate. Extracted amniotic fluid with amniotic fluid spectrophotometer scanner