目的探讨连续性血液净化在重症监护病房中的应用。方法在抗感染、机械通气、支持疗法等常规综合治疗的同时应用CBP救治ICU中19例ARF、MODS患者。结果 19例患者中,救治成功15例,患者病情好转,生命体征及意识状态明显改善,生化结果、pH、电解质趋于正常,生命体征稳定后转入普通病房继续治疗。2例因合并严重肺部感染并发多脏器功能衰竭而死亡,1例因心肺复苏后脑功能衰竭无改善而死亡,1例因经济原因自动出院。结论对ICU患者及早进行CBP可避免发生不可逆性脏器功能损害,提高抢救成功率。 Objective To investigate the application of continuous blood purification in intensive care unit. Methods A total of 19 patients with ARF and MODS in the ICU were treated with CBP while anti-infection, mechanical ventilation, and supportive therapies. Results Of the 19 patients, 15 cases were successfully treated. The patient’s condition improved, vital signs and consciousness improved significantly. Biochemical results, pH and electrolyte tended to be normal. After the vital signs were stabilized, they were transferred to the general ward for further treatment. Two patients died of complicated pulmonary infection complicated with multiple organ failure. One patient died of no improvement of cerebral failure after cardiopulmonary resuscitation. One patient was discharged automatically due to economic reasons. Conclusion Early ICU patients with CBP can prevent irreversible organ dysfunction and improve the success rate of rescue.