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T淋巴细胞群呈异质性,是具有各种功能的细胞,包括参与迟发性变态反应的效应细胞、细胞毒细胞、辅助及抑制性细胞。在小鼠中,根据其淋巴细胞表面同种异型抗原Ly 1、2、3的有无而区分具有不同功能的T细胞亚群。最近,Moretta等提出人类T淋巴细胞可按照其有否各种免疫球蛋白的Fc段受体进行分类:Tr细胞带IgG-Fc受体,Tμ细胞带IgM-Fc受体,Tα细胞带IgA-Fc受体,Tε细胞带IgE—Fc受体以及Tφ细胞不带任何Ig的Fc受体。由于Tα和Tε细胞新近才被发现,性质还不清楚,故本文重点介绍Tr、Tμ细胞的特征及其与胃肠道疾病的可能关系。两种亚群细胞的特性
T lymphocyte populations are heterogeneous and are cells with various functions, including effector cells, cytotoxic cells, helper and suppressor cells involved in delayed-onset allergic reactions. In mice, T lymphocyte subsets with different functions were distinguished based on the presence or absence of lymphocyte surface allotypic antigens Ly 1, 2, Recently, Moretta et al. Proposed that human T lymphocytes be classified according to whether they have Fc receptors for various immunoglobulins: Tr cells with IgG-Fc receptors, Tμ cells with IgM-Fc receptors, Tα cells with IgA- Fc receptors, Tε cells with IgE-Fc receptors and T receptors without any Ig. Since Tα and Tε cells have only recently been discovered, the nature of which remains unclear, this article focuses on the characteristics of Tr, Tμ cells and their possible relationship with gastrointestinal diseases. Characteristics of two subpopulations