内皮祖细胞是内皮细胞的前体细胞 ,在某些生理、病理状态下可随血流至相应组织 ,分化为内皮细胞 ,并进一步形成血管。内皮祖细胞不仅参与胚胎发育的血管发生 ,而且在成人机体的血管新生中起重要的作用。研究内皮祖细胞的生物学特性、动员、归巢及分化机制将为临床治疗缺血性疾病、创伤修复及抑制肿瘤生长提供理论依据。 Endothelial progenitor cells are the precursors of endothelial cells. Under certain physiological and pathological conditions, endothelial progenitor cells can differentiate into endothelial cells with blood flow to corresponding tissues and further form blood vessels. Endothelial progenitor cells are not only involved in angiogenesis in embryonic development, but also play an important role in angiogenesis in adult human body. Studying the biological characteristics, mobilization, homing and differentiation of endothelial progenitor cells will provide a theoretical basis for the clinical treatment of ischemic diseases, wound healing and tumor growth inhibition.