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本文采用高效液相色谱法,测定口服正常治疗剂量的酮基布洛芬受试者的血浆药物浓度。以蔡普生作内标。于酸性条件下沉淀血浆中蛋白后,用乙醚反复萃取,以峰高比定量。本品的工作曲线线性关系良好。
In this paper, high-performance liquid chromatography was used to determine the plasma drug concentration of ketoprofen in oral normal therapeutic doses. To Tsai Pusheng internal standards. The protein in plasma was precipitated under acidic conditions and repeatedly extracted with ether to quantify the peak height ratio. The working curve of this product has a good linear relationship.