论文部分内容阅读
目的观察杜仲叶饮片联合氨氯地平治疗老年高血压的临床疗效.方法选取2013-2014年在谷城县城关镇卫生院医院内科住院的96例高血压患者,按随机数字表法分为治疗组(48例)和对照组(48例).对照组口服氨氯地平单一治疗,治疗组在对照组的基础上加服杜仲叶饮片,均治疗30d.观察两组患者的血压改善情况及不良反应.结果治疗30d后,治疗组显效29例、有效16例、无效3例,对照组分别为16、21、11例,两组治疗效果间差异有统计学意义(Z=-2.26,P〈0.05).治疗组1例轻度头痛、头晕;对照组5例出现变态反应,轻度头晕;两组肝肾功能检查均无异常.结论杜仲叶饮片联合氨氯地平治疗老年高血压临床疗效确切,降压效果稳定,不良反应少,无肝肾损害,疗效优于单一应用氨氯地平治疗.值得临床推广使用. “,”Objective To observe the clinical curative effect ofEucommia Folium decoction pieces combined with amlodipine in the treatment of senile hypertension. Methods 96 patients with hypertension hospitalized in Gucheng Country Health Center of Hubei Province from 2013-2014 were selected and divided into the treatment group (48 cases)and thecontrol group (48 cases)according to random number table. The control group took only amlodi-pine orally, while the treatment group took arnlodipine plus Eucommia Folium decoction pieces. Both of the treatment lasted for 30d. Then this study observed the improvement of blood pressure and adverse reaction of the two groups. Results After 30 days treatment, 29 cases showed a conspicuous effect, 16 cases effective and 3 cases invalid in the treatment group, whereas the data was 16,21,11 in the control group. The difference was statistically significant between the two groups of patients (Z= -2.26, P〈0. 05). In terms of adverse reacti-on: 1 case in treatment group suffered slight headache and dizziness; in control group, 5 cases appeared allergic reaction and slight dizziness;no abnormal was found in hepatic and renal function in the two groups. Conclusion The union method of Eucommia Folium decoct-ion pieces combined with amlodipine in the treatment of senile hypertension shows definite curative effect with stable antihypertensive eficacy, less adverse reaction and little hepatic and renal damage, which is superior to single amlodipine. Therefore,it is worth popularization and application in clinic.