急性重症药物中毒的患者病情危重,需及时恰当地处理。本文介绍治疗16例急性危重药物中毒的经验,并结合有关文献讨论如下。1 临床资料 患者16例,男6例,女10例,年龄16～49岁,平均27.65岁。13例为严重镇静催眠药中毒,入院时8例深昏迷,1例浅昏迷,1例服用利福平,1例由于急性四氯化碳中毒,1例误服铬酸钾。7例合并休克,9例并发呼吸抑制,5例并发急性肾功能衰竭,3例并发严重肝损伤。 Patients with acute severe drug poisoning are critically ill and need to be properly and promptly treated. This article describes the treatment of 16 cases of acute critically ill drug poisoning experience, combined with the literature discussed below. A clinical data of 16 patients, 6 males and 10 females, aged 16 to 49 years, an average of 27.65 years. 13 cases were severe sedative hypnotic poisoning, 8 cases were in deep coma at admission, 1 was shallow coma, 1 was taking rifampicin, 1 case was acutely poisoned with carbon tetrachloride, 1 case was inadvertently served with potassium chromate. Seven patients had shock, nine had respiratory depression, five had acute renal failure, and three had severe liver injury.