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目的探讨早产儿囊性脑室周围白质软化症(cPVL)与低碳酸血症及机械通气的关系。方法比较cPVL与非cPVL早产儿(各10例)生后3d内发生的低碳酸血症(至少2次PaCO2<3.33kPa)情况以及每天机械通气参数,两组在胎龄、出生体重、性别及临床情况方面统计均无差异。结果cPVL组发生低碳酸血症几率为70%,明显高于非cPVL组的20%(P=0.02),而两组每天机械通气参数无差异。结论早产儿cPVL的发生与低碳酸血症有关,似乎与过度通气无关。
Objective To investigate the relationship between cystic periventricular leukomalacia (cPVL) and hypocapnia and mechanical ventilation in premature infants. Methods The hypocalcemia (at least 2 times PaCO2 <3.33kPa) and the daily mechanical ventilation parameters of cPVL and non-cPVL preterm infants (10 cases each) were compared between the two groups in terms of gestational age, birth weight, sex and No statistical differences in clinical conditions. Results The incidence of hypocapnia in cPVL group was 70%, which was significantly higher than that in non-cPVL group (P = 0.02). There was no difference in daily mechanical ventilation parameters between the two groups. Conclusions The occurrence of cPVL in preterm infants is associated with hypocapnia and seems to be independent of hyperventilation.