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目的:了解重症监护病房(ICU)常用抗菌药及临床应用。方法:对我院2011年1～6月ICU出院患者的用药及细菌耐药情况进行回顾性调查,对用药种类、用药频度和合理用药情况进行统计分析。结果:我院ICU2011年1～6月出院病历147份,其中41例死亡。106例非死亡病例抗菌药使用率100%,使用抗菌药29个品种,其中氟康唑、替考拉宁、头孢哌酮/舒巴坦、左氧氟沙星的用药倾向性大。63例做病原学检测,占使用抗菌药病例的59.43%。结论:应加强ICU细菌耐药性的监测,限制抗茵药的不合理使用,控制性使用头孢哌酮/舒巴坦等超广谱抗菌药,以减少细菌耐药性的产生。
Objective: To understand the commonly used antimicrobial agents in intensive care unit (ICU) and its clinical application. Methods: A retrospective survey was conducted on the medication and bacterial resistance of discharged patients in ICU from January to June in 2011. Statistical analysis was made on the types of drugs, the frequency of medication and the rational use of drugs. Results: There were 147 medical records in ICU from January to June in 2011, of which 41 cases died. 106 cases of non-death cases of antibacterial use rate of 100%, the use of antimicrobial drugs 29 varieties, including fluconazole, teicoplanin, cefoperazone / sulbactam, levofloxacin medication predisposition. 63 cases of etiological testing, accounting for 59.43% of cases using antibacterials. Conclusion: The surveillance of bacterial resistance in ICU should be strengthened to limit the unreasonable use of anti-inflammatory drugs and to control the use of extended-spectrum antibacterials such as cefoperazone / sulbactam to reduce bacterial resistance.