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体外抑菌实验证明，清热化毒丹（微丸）与清热化毒丸（蜜丸）对肺炎双球菌、金黄色葡萄球菌、痢疾杆菌和大肠肝菌四菌株，均具有中度敏感的抑菌作用。体内实验小白鼠灌胃给药证明，微丸与蜜丸均能明显抑制二甲苯所致耳肿胀（抗炎作用），减少冰醋酸所致扭体反应次数（镇痛作用），减少小鼠自发活动次数（镇静作用）。在含生药量近似的情况下，上述药理作用微丸与蜜丸间无显著差异（P＞0.05）。
In vitro antibacterial experiments showed that Qingre Huadudan (Pellets) and Qingrehuadu Pills (Mel Pills) are moderately sensitive to the four strains of Streptococcus pneumoniae, Staphylococcus aureus, Shigella and Escherichia coli. effect. The intragastric administration of intragastric administration to mice showed that both pellets and honeyed pills can significantly inhibit xylene-induced ear swelling (anti-inflammatory effect), reduce the number of writhing reactions caused by glacial acetic acid (analgesic effect), and reduce spontaneousness of mice. Number of activities (sedation). In the case of similar crude drug doses, there was no significant difference between the pharmacological action pellets and honey pills (P>0.05).