【摘 要】
:
Palladium-catalyzed oxidative formal [4 + 1] annulation of pyridine-substituted acrylonitriles toward di-vergent fused N-heterocycles synthesis is reported. The heterodifunctionalization reaction with Cu(OAc)2 and urea as the nitrogen source accesses to n
【机 构】
:
Key Laboratory of Organo-Pharmaceutical Chemistry of Jiangxi Province,Gannan Normal University,Ganzh
论文部分内容阅读
Palladium-catalyzed oxidative formal [4 + 1] annulation of pyridine-substituted acrylonitriles toward di-vergent fused N-heterocycles synthesis is reported. The heterodifunctionalization reaction with Cu(OAc)2 and urea as the nitrogen source accesses to nitrile-substituted pyrazolo[1,5-a]pyridines in moderate to good yields, while the homodifunctionalization reaction with FeBr3 leads to synthesis of nitrile-substituted indolizines in excellent yields.
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