近年来已知人类癌症的起源涉及致癌基因。到目前为止,人们已鉴定出20多个致癌基因,并在一些癌细胞中发现了致癌基因的过量拷贝。例如美国国立肿瘤研究所的Gallo小组等已经证实myc基因可在培养的人白血病细胞株中进行扩增。由于获得这些培养细胞株的原癌细胞也携带有myc基因的过量拷贝,表明这并非培养过程中人为造成的。许多人曾致力于成神经细胞瘤的研究,这是一 It has been known in recent years that the origin of human cancers involves oncogenes. So far, more than 20 oncogenes have been identified and over-copies of oncogenes have been found in some cancer cells. For example, the Gallo group of the National Cancer Institute has confirmed that myc gene can be amplified in cultured human leukemia cell line. Since the proto-cancer cells that obtained these cultured cell lines also carry an over-copy of the myc gene, this is not an artifact in the culturing process. Many people have been committed to the study of neuroblastoma, which is one