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为评价腺外浸润的晚期甲状腺癌的手术疗效和预后,回顾性分析了16例手术治疗的甲状腺癌病例,其中侵及范围为气管、食管、喉、喉返神经、下咽和颈部大血管等。1例行根治性手术,其它均行功能性手术,对喉、气管、食管及下咽的缺损进行了修复重建。全部病例均有1年以上的随访。结果发现,11例喉气管重建者均拔管;2例下咽食管成形者吞咽功能良好。1例术后4年双肺转移死亡,余15例未发现复发及转移。其中生存1年、3年、5年、10年和15年者分别为16例、14例、7例、3例和1例。探讨了晚期甲状腺癌腺外浸润范围对确定手术方式的意义及术后综合治疗的重要性。尽管晚期病变腺外浸润周围诸多重要器官和结构,但积极行功能性外科手术仍有助于提高疗效及患者生存质量。
To evaluate the efficacy and prognosis of extra-adenodal invasive advanced thyroid cancer, 16 cases of surgically treated thyroid cancer were retrospectively analyzed. The invasive range included trachea, esophagus, larynx, recurrent laryngeal nerve, hypopharyngeal and cervical large vessels. Wait. One case underwent radical surgery and all other functional surgeries performed reconstruction of the laryngeal, tracheal, esophageal and hypopharyngeal defects. All cases have more than one year of follow-up. The results showed that 11 cases of laryngeal tracheal reconstruction were extubation; 2 cases of hypopharyngeal esophageal shapers had good swallowing function. One patient died of lung metastasis 4 years after surgery, and 15 patients had no recurrence or metastasis. Among them, 16 cases, 14 cases, 7 cases, 3 cases and 1 case survived 1 year, 3 years, 5 years, 10 years and 15 years. The significance of the extra-invasive invasive range of advanced thyroid cancer in determining the surgical approach and the importance of postoperative comprehensive treatment were explored. Although advanced lesions infiltrate many vital organs and structures outside the gland, active functional surgery still helps to improve the efficacy and quality of life of patients.