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前列腺癌是男性癌症死亡的主要原因之一。雄激素阻断疗法是治疗晚期前列腺癌的主要方法。这种方法在治疗雄激素依赖性前列腺癌非常有效。然而,这种恶性肿瘤最终会成为雄激素非依赖性,抗雄激素药物逐渐失去作用,对于雄激素非依赖性前列腺癌的治疗,目前没有一个行之有效的方法,是临床上最棘手的问题之一。如何有效治疗雄激素非依赖性前列腺癌成为目前医学研究的重点之一。端粒作为染色体末端的保护帽,是染色质的专
Prostate cancer is one of the major causes of cancer death in men. Androgen blockade therapy is the main method of treatment of advanced prostate cancer. This method is very effective in the treatment of androgen-dependent prostate cancer. However, this malignancy eventually becomes androgen-independent, anti-androgenic drugs are gradually losing their effect and currently there is not an effective method for the treatment of androgen-independent prostate cancer, which is the most clinically intractable problem one. How to effectively treat androgen-independent prostate cancer has become one of the focuses of medical research at present. Telomere, as a protective cap at the end of chromosomes, is a specialized chromatin