越来越多的研究表明,脂肪组织是一个活跃的内分泌器官,其分泌多种脂肪因子,在代谢稳态维持中有重要的作用。日本学者Fukuhara A等利用差异显示的方法比较皮下脂肪和内脏脂肪的多种PCR产物时,发现在内脏脂肪特异性的高表达一种物质,序列测定证实其cDNA片段与编码前B细胞集落增强 A growing body of research shows that adipose tissue is an active endocrine organ that secretes a variety of adipokines and plays an important role in the maintenance of metabolic homeostasis. Japanese scholar Fukuhara A et al. Used differential display to compare multiple PCR products of subcutaneous fat and visceral fat and found that a substance specifically expressed in visceral fat was found. Sequencing confirmed that its cDNA fragment was enhanced with those encoding pre-B cell colonies