论文部分内容阅读
目的了解长春市孕产妇风疹抗体水平,评估孕产妇对风疹的易感性,为控制先天性风疹综合征(Congenital Rubella Syndrome,CRS)提供科学依据。方法2006年4月至2007年6月,在吉林大学第二医院妇产科住院部,随机选取21~41岁的孕产妇180人,收集其分娩的新生儿脐带血180份进行血清流行病学调查。结果孕产妇风疹IgG抗体总阳性率为82.78%。风疹抗体阳性率随着年龄增长而下降。各年龄组间抗体阳性率差异有统计学意义。而按地区、孕周、自然流产史等因素分组,差异无统计学意义。结论风疹发病与年龄有关,随着年龄增长抗体阳性率有下降趋势。长春市有17.22%的孕产妇有患风疹的危险。而且随着各省市、地区风疹计划免疫的实施,风疹现有的流行局势可能被打破,会出现风疹在较大年龄组中爆发流行的新局势。
Objective To understand the level of rubella antibody in pregnant women in Changchun and assess the susceptibility of pregnant women to rubella and provide a scientific basis for the control of Congenital Rubella Syndrome (CRS). Methods From April 2006 to June 2007, 180 pregnant women aged 21-41 years were selected randomly from the Department of Obstetrics and Gynecology, Second Hospital of Jilin University to collect 180 newborn umbilical cord blood from their children for serological epidemiology survey. Results The total positive rate of rubella IgG antibody in pregnant women was 82.78%. Rubella antibody positive rate decreased with age. The antibody positive rate among all age groups had statistical significance. By region, gestational age, history of spontaneous abortion and other factors, the difference was not statistically significant. Conclusion The incidence of rubella is related to age. The positive rate of antibody decreases with age. Changchun City, 17.22% of pregnant women are at risk of rubella. And with the implementation of immunization against rubella in all provinces, municipalities and regions, the current prevalence of rubella may be broken and a new situation of epidemics of rubella in older age groups will emerge.