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目的研究及观察急性呼吸道感染患儿红细胞免疫与黏膜纤毛结构的变化情况,为疾病的诊断与治疗提供依据。方法选取2014年2月-2015年6月于医院诊治75例急性呼吸道感染患儿为观察组,选取同时期75名健康同龄儿童为对照组,将两组儿童的红细胞免疫与黏膜纤毛结构指标进行检测与比较,并比较观察组患儿呼吸道感染不同严重程度与感染部位检测结果,数据采用SAS5.0软件进行统计分析。结果观察组患儿红细胞免疫黏附促进因子(FEER)为(60.25±3.98)%、协同肿瘤红细胞花环率(ATER)为(55.34±4.70)%、直向肿瘤红细胞花环(DTER)(29.62±2.88)%及红细胞C3b受体花环(RBC-C3bR)为(15.65±1.74)%,均低于对照组,黏膜纤毛结构指标异常率观察组高于对照组,差异均有统计学意义(P<0.05);呼吸道感染不同严重程度与感染部位者的检测结果也存在明显差异,差异有统计学意义(P<0.05)。结论急性呼吸道感染患儿红细胞免疫处于较差的状态,而黏膜纤毛结构异常情况也较明显,应给予充分重视。
Objective To study and observe the change of erythrocyte immunity and mucociliary structure in children with acute respiratory infection and provide the basis for the diagnosis and treatment of the disease. Methods From February 2014 to June 2015, 75 children with acute respiratory infection were selected as the observation group in the hospital. 75 healthy children of the same period were selected as the control group. Erythrocyte immunization and mucociliary structure index Detection and comparison, and compared the observation group of children with respiratory tract infection of different severity and detection of infection site data using SAS5.0 software for statistical analysis. Results The rate of erythrocyte adhesion molecule (60.25 ± 3.98)%, the rate of erythrocyte rosette (ATER) and the direct tumor erythrocyte rosette (DTER) in the observation group were (29.62 ± 2.88) and % And erythrocyte C3b receptor rosette (RBC-C3bR) were (15.65 ± 1.74)%, respectively, which were lower than those in the control group. The abnormal rate of mucociliary structural index was higher in the observation group than in the control group (P <0.05) There were also significant differences in the detection results of respiratory tract infection patients with different severity and location of infection, the difference was statistically significant (P <0.05). Conclusion The erythrocyte immunity of children with acute respiratory infection is in a poor state, and the mucosal cilia structural abnormalities are also more obvious, which should be given full attention.