论文部分内容阅读
为了研究糖尿病患者体内微量元素的变化，采用原子吸收石墨炉法及火焰法分别对链脲佐菌素诱导的糖尿病大鼠血（血清）、肝及肾中的铬、锌、铜的含量进行了３周的观察。结果表明：在整个观察期间，与正常大鼠相比，糖尿病大鼠肝铬含量明显升高，肾铬含量明显下降；肝、肾中的锌、铜及血清铜含量均呈不同程度的升高。在所观察的３周内，未发现糖尿病大鼠血（血清）、肝、肾中铬、锌、铜含量随病程而变化；而大鼠体内微量元素的变化与其血糖值关系密切，肝中铬、锌、铜含量及肾中锌、铜含量与血糖呈正相关关系，肾铬含量与之呈负相关关系。因而，改善糖尿病大鼠的血糖情况可能会在一定程度上控制其体内微量元素的紊乱。
In order to study the changes of microelements in diabetic patients, the levels of chromium, zinc and copper in blood (serum), liver and kidney of streptozotocin-induced diabetic rats were measured by atomic absorption graphite furnace and flame method respectively 3 weeks of observation. The results showed that during the whole observation period, compared with normal rats, the content of hepatic chromium in diabetic rats increased significantly and the content of chromium in kidney decreased significantly. The content of copper, copper and serum in liver and kidney increased to some extent . During the 3 weeks of observation, no changes in blood (serum), chromium, zinc and copper contents in the liver and kidney were observed in the diabetic rats, but the changes of trace elements in the rats were closely related to the blood glucose level. , Zinc, copper content and kidney zinc, copper content and blood glucose was positively correlated, and kidney chromium content was negatively correlated. Therefore, to improve blood glucose in diabetic rats may be to some extent, the control of their body trace element disorders.