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为比较准分子激光原位角膜磨镶术与准分子激光角膜切削术治疗高度近视的疗效，对２８８眼行ＰＲＫ手术及２９眼行ＬＡＳＩＫ手术，分别分为两组，观察１～１２月。结果：ＰＲＫ组术后一年裸视大于等于０５占７９４％，大于等于０８占６３２％，其中二组大于等于０５占５８３％，大于等于０８占３１６％。ＬＡＳＩＫ组术后一年裸视大于等于０５占６９２％，大于等于０８占５３１％，其中，二组大于等于０５占６６７％，大于等于０８占５０％。最佳矫正视力大于等于术前者ＰＲＫ组占９３７％，ＬＡＳＩＫ组占９２％。ＰＲＫ组角膜混浊一月时最重，一年时最轻。ＬＡＳＩＫ组无角膜混浊发生。实际矫正度在预计矫正度＋／－１Ｄ内者ＰＲＫ和ＬＡＳＩＫ分别占５２％和５１８％。结论：ＬＡＳＩＫ虽然由于微角膜切开刀的使用而较复杂，但对于大于－１００Ｄ的近视，是一种较ＰＲＫ好的手术方法。
To compare the efficacy of laser in situ keratomileusis and excimer laser keratomileusis for the treatment of high myopia, 288 eyes underwent PRK surgery and 29 eyes underwent LASIK. The patients were divided into two groups and observed from January to December. Results: One year after operation in PRK group, 05 accounted for 794% or more, 08 accounted for 632%, two groups of 05 accounting for 583%, greater than or equal to 0 8 accounted for 31 6%. One year after operation in LASIK group, 05 accounted for 692% or more, 08 or more accounted for 531%, of which, two groups of 05 accounted for 667%, greater than or equal to 08 Accounting for 50%. The best corrected visual acuity was ≥737% in PRK group and 92% in LASIK group. PRK corneal opacity was heaviest in January, the lightest year. LASIK group no corneal opacity. PRK and LASIK accounted for 52% and 51.8% of the actual correction within +/- 1D. Conclusion: Although LASIK is more complicated due to the use of a microkeratome, it is a better surgical method than PRK for myopia greater than -100D.