1临床资料患者男,65岁,退休工人。双下肢胫前出现皮疹渐增大2月。2年前因食欲较前增多,有心悸气短、怕热、急躁等症状在外院诊断为甲亢,给予他巴唑、心得安等治疗,症状缓解。否认食物药物过敏史,家族中无类似病史。体检:T36.5℃,P83次/min,R17次/min,BP120/75mmHg,双眼未见明显突出,睑裂不增宽,双侧甲状腺未触及肿大,心、肝、脾、肺、肾及神经系统检 1 clinical data patient male, 65 years old, retired workers. Lower extremity anterior tibia rash increased in February. 2 years ago due to an increase in appetite, palpitation shortness of breath, febrile, impatient and other symptoms in the hospital diagnosed as hyperthyroidism, given methimazole, propranolol and other treatment, relieve symptoms. Denied the history of food and drug allergies, no similar family history. Physical examination: T36.5 ℃, P83 times / min, R17 times / min, BP120 / 75mmHg, no obvious prominence in both eyes, palpebral fissure does not broaden, bilateral thyroid enlargement, heart, liver, spleen, lung and kidney And nervous system examination