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目的:探讨中药肿节风联合金因肽在放射性口腔黏膜炎患者中的临床治疗效果。方法:选取2015年1月—2015年10月广西壮族自治区桂林医学院附属医院诊治的80例放射性口腔黏膜患者,随机将患者分为对照组和试验组,对照组采用金因肽治疗,试验组在对照组基础上联合中药肿节风颗粒治疗,比较两组临床疗效。结果:试验组总有效率为95%,显著高于对照组(85%)(P<0.05);试验组放射性口腔黏膜炎愈合时间、疼痛评分,显著低于对照组(P<0.05)。治疗后,两组患者血清指标均下降,试验组的TNF-α、IL-6、IL-8低于对照组,差异有统计学意义(P<0.05)。结论:放射性口腔黏膜炎治疗时在金因肽治疗基础上联合中药肿节风治疗效果显著,值得推广应用。
Objective: To investigate the clinical efficacy of traditional Chinese medicine combined with tympanites and gold peptide in patients with radiation-induced oral mucositis. Methods: Eighty patients with radioactive oral mucosa diagnosed and treated in Guilin Medical College Affiliated Hospital of Guangxi Zhuang Autonomous Region from January 2015 to October 2015 were randomly divided into control group and experimental group, while control group was treated with gold peptide. The experimental group On the basis of the control group, combined with the treatment of traditional Chinese medicine Fengjiefeng granules, the clinical curative effect was compared between the two groups. Results: The total effective rate of the experimental group was 95%, which was significantly higher than that of the control group (85%) (P <0.05). The healing time and pain score of the radiation oral mucositis in the experimental group were significantly lower than those in the control group (P <0.05). After treatment, the serum indexes of both groups decreased, and the levels of TNF-α, IL-6 and IL-8 in the experimental group were lower than those in the control group (P <0.05). Conclusion: The treatment of radioactive oral mucositis in the treatment of gold peptide on the basis of treatment of traditional Chinese medicine swollen wind is significant, it is worth promoting the application.