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目的 进一步提高原发性胆囊癌的早期诊断水平和对本病的发病、病理分期及转归的认识.方法 对1956～1998年收治的679例胆囊癌患者的病例资料进行回顾性研究.结果 679例胆囊癌中,女性与男性之比约为3:1.多数病例诊断时已属晚期,胆囊癌手术452例,发现早期病变46例(6.8%).679例中,手术率66.6%(18.2%～78.2%),切除率30.3%(20.0%～36.0%).病理分期199例中,Ⅰ—Ⅱ期获早期诊断者仅7例(11.1%～31.6%).结论 加强对本病的发病、病理分期及转归的认识以及各种检查手段的合理运用,是获得早期诊断及改善预后的基本途径.
Objective To further improve the early diagnosis of primary gallbladder carcinoma and its understanding of the pathogenesis, pathological staging and prognosis of the disease. Methods Retrospective study of 679 cases of gallbladder cancer patients admitted from 1956 to 1998.Results Cases of gallbladder carcinoma, the ratio of women to men is about 3:1. Most cases have been diagnosed at the time of late, 452 cases of gallbladder cancer surgery, early lesions found in 46 cases (6.8%). 679 cases, the surgery rate of 66.6% (18.2 %～78.2%), the resection rate was 30.3% (20.0%～36.0%). Among the 199 cases of pathological stage, only 7 cases (11.1%～31.6%) were diagnosed early in stage I-II. Conclusions to strengthen the incidence of this disease The understanding of pathological staging and prognosis, as well as the rational use of various examination methods, is the basic way to obtain early diagnosis and improve the prognosis.