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现在认为,本质未明的肾脏病的发展,急性或潜伏性病毒感染可起一定作用。据文献资料,肾小球肾炎在肾发现HBsAg的频率为2～56％,这样大的波动与诊断方法的灵敏度有关。作者研究肾组织有HBsAg沉积的肾脏病的临床经过,从1984～1987年646例肾穿刺活检中,查出有HBsAg沉积者14例(2.2％),男12例,女2例。年龄16～47岁。其中慢性肾小球肾炎9例(膜—增生性5例,血管系膜—增生性4例),慢性小管间质性肾炎5例。4～12年以前曾患急性肝炎9例,无肝炎病史5例。肝穿刺活检13例,检出慢性迁延性病毒性肝炎10例。肝功能都正常。血也清查出HBsAg只1例。肾脏病
It is now believed that the development of an unexplained kidney disease, acute or latent viral infection may play a role. According to literature, glomerulonephritis found in the kidney HBsAg frequency of 2 to 56%, such a large fluctuation and diagnostic sensitivity. The authors studied the clinical course of nephrotic kidney disease with deposition of HBsAg. From 1984 to 1987, 646 renal biopsy samples showed that there were 14 (2.2%) HBsAg-positive patients, 12 males and 2 females. Age 16 to 47 years old. Among them, there were 9 cases of chronic glomerulonephritis (5 cases of membranoproliferation, 4 cases of mesangial - proliferative) and 5 cases of chronic tubulointerstitial nephritis. 4 to 12 years ago had acute hepatitis in 9 cases, no history of hepatitis 5 cases. Thirteen liver biopsy specimens were detected in 10 patients with chronic persistent viral hepatitis. Liver function are normal. Blood clear also found only 1 case of HBsAg. kidney disease