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对急性心肌梗塞进行溶栓疗法可望开通闭塞的冠状动脉。大剂量尿激酶(UK)的静脉溶栓法(IVCR)与冠状动脉内溶栓法(PTCR)对闭塞冠脉的再通率无差别。前者有快速投药的优点,然因未作冠脉造影,难以判断是否再通。本文总结56例急性心肌梗塞早期患者的紧急冠脉造影所见与临床症状、心电图 ST 段及血清肌酸激酶(CK)的变化,探讨判断冠状动脉再通的无创性指标。对象与方法:对象为56例急性穿壁性心肌梗塞早期入院患者(发病3.4±1.5小时),为作 PTCR 进行了紧急冠脉造影。前壁梗塞计31例,下壁梗塞计25例。平均年龄57±9岁。男48例、女8例.溶栓疗
Thrombolytic therapy for acute myocardial infarction is expected to open the occluded coronary artery. There was no difference in the recanalization rate of occluded coronary artery between intravenous thrombolysis (IVCR) with high-dose urokinase (UK) and intra-coronary thrombolysis (PTCR). The former has the advantages of rapid dosing, but because of coronary angiography, it is difficult to determine whether the recanalization. This article summarizes the findings of acute coronary angiography and clinical symptoms, ST segment of electrocardiogram and serum creatine kinase (CK) in 56 patients with acute myocardial infarction in the early stage, and discusses the noninvasive indexes to judge the recanalization of coronary artery. PARTICIPANTS AND METHODS: Subjects were 56 hospitalized patients with early-stage acute transmural myocardial infarction (onset 3.4 ± 1.5 hours) undergoing emergency coronary angiography for PTCR. 31 cases of anterior wall infarction and 25 cases of inferior wall infarction. The average age of 57 ± 9 years old. 48 males and 8 females. Thrombolytic therapy