Prostate cancer risk prediction models in Eastern Asian populations: current status, racial differen

来源 :亚洲男性学杂志(英文版) | 被引量 : 0次 | 上传用户:asdfsadfsad
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Prostate cancer (PCa) risk calculators (RCs) with prostate-specific antigen (PSA) and other risk factors can greatly improve the accurate prediction of potential risk of PCa compared to PSA.The European Randomized Study of Screening for PCa Risk Calculator (ERSPC-RC) and the Prostate Cancer Prevention Trial Risk Calculator (PCPT-RC) are developed on the Western population.However,the Western RCs showed limited diagnostic efficacy in the Eastern Asian population,mainly due to racial differences between the two populations.We aimed to review the application of Western RCs and Eastern Asian RCs in Eastern Asian cohorts and to identify the characteristics and efficacy of these RCs.
其他文献
Dear Editor,rnInfertility affects about 48.5 million couples worldwide,and a male disorder is estimated to be a causative or contributing factor in 20%-50% of cases.1 Notably,increasing data support the view that obese men are at higher risk offertility d
期刊
We performed this meta?analysis to evaluate the predictive value of different parameters in the sperm retrieval rate (SRR) of microdissection testicular sperm extraction (TESE) in patients with nonobstructive azoospermia (NOA). All relevant studies were s
The Y-located testis-specific protein Y-encoded (TSPY) and its X-homologue TSPX originated from the same ancestral gene,but act as a proto-oncogene and a tumor suppressor gene,respectively.TSPY has specialized in male-specific functions,while TSPX has ass
Differences in intravaginal ejaculation latency reflect normal biological variation,but the causes are poorly understood.Here,we investigated whether variation in ejaculation latency in an experimental rat model is related to altered sympathetic nervous s
Leptin,an adipocyte-derived hormone,serves numerous physiological functions in the body,particularly during puberty and reproduction.The exact mechanism by which leptin activates the gonadotropin-releasing hormone (GnRH) neurons to trigger puberty and rep
This study aimed to assess the role of the National Comprehensive Cancer Network (NCCN) risk classification in predicting biochemical recurrence (BCR) after radical prostatectomy (RP) in Chinese prostate cancer patients.We included a consecutive cohort of