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硝酸甘油用于治疗心绞痛至今已有120年的历史,仍不失为较佳的心绞痛治疗药物。硝酸甘油口服后在胃肠道大部分被破坏,而舌下给药虽作用明显但时间短暂,皮下或静脉注射虽能迅速发挥药效,但因作用时间不长,使用不便,非属必要很少采用。因此,近几年来,许多人对硝酸甘油软膏产生了极大兴趣。有人在动物及健康人身上观察了局部皮肤涂敷硝酸甘油油膏后的吸收情况和药效学情况。有的研究证明硝酸甘油油膏能明显增加心绞痛患
Nitroglycerin for the treatment of angina has been 120 years of history, is still a good angina treatment drugs. After oral administration of nitroglycerin most of the gastrointestinal tract is destroyed, while the role of sublingual administration is obvious but a short time, although subcutaneous or intravenous injection can quickly play a pharmacodynamic effect, but because of the role of time is not long, inconvenient to use, it is not necessary Less used. Therefore, in recent years, many people have great interest in nitroglycerin ointment. Some people in animals and healthy people who observed the local skin after the application of nitroglycerin ointment absorption and pharmacodynamics. Some studies have shown that nitroglycerin ointment can significantly increase angina pectoris