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目的探讨乌鲁木齐市维吾尔族(以下简称:维族)、汉族男性弱精子症的危险因素,为维、汉族男性弱精子症的病因研究、预防干预及生殖健康服务工作提供依据。方法对维、汉族男性弱精子症患者及维、汉族男性正常健康体检者,进行问卷调查及实验室检查。并将研究对象分为四组,分别为:维、汉族男性弱精子症组,维、汉族男性健康体检组(后称:维、汉族正常组)。分别对维、汉族男性弱精子症组各166人与维、汉族正常组各166人,进行单因素Logistic回归分析,初步筛选出有影响的危险因素,再进行多因素Logistic回归分析,进一步精选出对维、汉族男性弱精子症有极大影响的因素,做出回归方程,并分析危险因素产生的原因。结果 1、对维族弱精子症而言,有关联的危险因素是饮酒史(OR=2.475,95%CI:1.283-4.773);对汉族弱精子症而言,有关联的危险因素是农药接触史(OR=0.454,95%CI:0.195-1.054),棉籽油的食用史(OR=2.115,95%CI:1.250-3.579)。2、维族弱精子症患者使其配偶有流产史不育的危险性高于维族正常组(OR=3.094,95%CI:1.149-8.332)。结论 1、维族男性少精子症而言,有关联的危险因素是末次排精时间;对汉族男性少精子症而言,有关联的危险因素是末次排精时间;对维族男性弱精子症而言,有关联的危险因素是饮酒史;对汉族男性弱精子症有关联的危险因素是农药接触史以及棉籽油的食用史。2、汉、维族男性少精子症患者和维族男性弱精子症患者均可使其配偶有流产。
Objective To explore the risk factors of Uygur (Uygur) and Han male infertility in Urumqi, and to provide the basis for the etiological research, preventive intervention and reproductive health service of male and female Han spermatozoa. Methods Questionnaires and laboratory tests were performed on male and female male patients with wean and Han Chinese male and female normal health examination. The subjects were divided into four groups: male and female male sperm weakness group, Victoria and Han male health examination group (later: Victoria and Han normal group). Sixty-six male and 58 normal Han controls were enrolled in this study. One-way logistic regression analysis was used to analyze the risk factors in Victoria male and Han male asthenospermia group and 166 normal controls respectively. Multivariate logistic regression analysis was used to further select Out of Wei, Han male asthenospermia have a significant impact factors, make regression equation, and analyze the causes of risk factors. For Uygur asthenospermia, the associated risk factor was alcohol consumption (OR = 2.475, 95% CI: 1.283-4.773); for Han asthenospermia, the associated risk factors were exposure history of pesticides (OR = 0.454, 95% CI: 0.195-1.054), consumption history of cottonseed oil (OR = 2.115, 95% CI: 1.250-3.579). 2, Uighur asthenospermia patients spouses have a higher risk of genital abortion than the normal Uygur group (OR = 3.094, 95% CI: 1.149-8.332). Conclusion 1, Uygur male oligzoospermia, the risk factor associated with the time of the last ejaculation; for Han male oligzoospermia, the risk factor associated with the last time of sperm ejection; Uygur men with asthenospermia , The associated risk factor is drinking history; the risk factors associated with asthenospermia in Han men are the history of exposure to pesticides and the consumption history of cottonseed oil. 2, Han, Uygur male patients with oligospermia and Uygur male patients with asthenospermia can make their spouses have abortion.