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目的研究分析急性胰腺炎诊断中检测降钙素原及C反应蛋白的价值以及对治疗的指导意义。方法选择急性胰腺炎患者76例,分为无感染组与有感染组,各38例。另选择非急性胰腺炎的健康组38例,比较三组降钙素原以及C反应蛋白的检测值。结果无感染组与有感染组患者降钙素原检测值显著高于健康组,差异具有统计学意义(P<0.01);有感染组患者的降钙素原检测值高于无感染组,差异具有统计学意义(P<0.05)。无感染组与有感染组患者C反应蛋白检测值显著高于健康组,差异具有统计学意义(P<0.01);有感染组患者C反应蛋白检测值高于无感染组,差异具有统计学意义(P<0.05)。结论急性胰腺炎的早期快速诊断可通过降钙素原与C反应蛋白的检测值客观的判断,同时对存在的感染具有较高的敏感度,可作为科学判断病情进展情况和预后情况的指标,值得在临床中推广应用。
Objective To study the value of detecting procalcitonin and C-reactive protein in the diagnosis of acute pancreatitis and to guide the treatment. Methods 76 patients with acute pancreatitis were divided into non-infected group and infected group, 38 cases each. Another 38 cases of non-acute pancreatitis health group, comparing the three groups of procalcitonin and C-reactive protein detection. Results The detection of procalcitonin in non-infected group and infected group was significantly higher than that in healthy group (P <0.01), and the detection of procalcitonin in infected group was higher than that in non-infected group Statistically significant (P <0.05). The detection value of C-reactive protein in non-infected group and infected group was significantly higher than that in healthy group, the difference was statistically significant (P <0.01); the detection value of C-reactive protein in infected group was higher than that in non-infected group, the difference was statistically significant (P <0.05). Conclusion The rapid early diagnosis of acute pancreatitis can be judged objectively by the detection value of procalcitonin and C-reactive protein, and has high sensitivity to the existing infection, which can be used as an index to judge the progress of the disease and the prognosis of the disease. It is worth to promote the clinical application.