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目的 :探讨中枢神经细胞瘤的影像学表现、诊断和治疗。方法 :分析2005年1月—2013年3月本院收治的7例中枢神经细胞瘤患者的临床资料,总结手术治疗经验,并对相关文献进行综述。结果 :7例患者中,男性4例,女性3例;6例肿瘤位于侧脑室前2/3,5例起源于室间孔附近的透明隔,1例起源于侧脑室侧壁;头颅MRI平扫T1WI多呈低信号为主的混杂信号,T2WI多呈高信号或稍高信号,增强MRI呈不均匀性强化。肿瘤完全切除6例,次全切除1例;术后放疗2例,化疗1例。术后院内死亡1例。随访时间为15至25个月,随访5例,失访1例。4例患者均预后良好,1例患者偏瘫,均未见肿瘤复发。结论 :显微外科手术是治疗中枢神经细胞瘤的首选方法,掌握手术技巧及注意事项可达到明显的治疗效果,同时可根据患者情况选择术后放疗。
Objective: To investigate the imaging manifestations, diagnosis and treatment of central neurocytoma. Methods: The clinical data of 7 patients with central neurocytoma treated in our hospital from January 2005 to March 2013 were analyzed. The experience of surgical treatment was summarized and the related literatures were reviewed. Results: Of the 7 patients, 4 were male and 3 were female. Six of the six tumors were located in the anterior part of the lateral ventricle, 2/3 and 5 cases originated in the transparent septum near the interventricular septum, and one case originated from the lateral ventricle wall. Scan T1WI were mostly low-signal-based mixed signal, T2WI mostly high signal or slightly higher signal, enhanced MRI showed heterogeneous enhancement. Complete resection of the tumor in 6 cases, subtotal resection in 1 case; postoperative radiotherapy in 2 cases, 1 case of chemotherapy. One patient died in hospital after operation. The follow-up time ranged from 15 to 25 months, 5 cases were followed up and 1 case was lost to follow-up. All 4 patients had good prognosis and 1 patient had hemiplegia. No tumor recurrence was found. Conclusion: Microsurgery is the preferred method for the treatment of central neurocytoma. To master the surgical techniques and precautions can achieve significant therapeutic effect. At the same time, we can choose the postoperative radiotherapy according to the patient’s condition.