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治疗充血性心力衰竭的最有效药物是洋地黄甙,利尿剂和血管扩张剂。有时也可应用拟交感神经药物如多巴胺、多巴酚丁胺等。据Brounwald意见,洋地黄甙是治疗心衰的最基本药物,并主张所有心衰病人,只要无反指征,均该应用。但临床上已充分证明洋地黄的弊端甚多,比如:该药的正性变力作用不强;最大有效量与中毒量非常接近;病态窦房结综合征、房室传导阻滞和室性心律失常的病人不宜使用;老年人因心率较慢,窦房结功能较差,用药时应慎重;此外,洋地黄甙的毒、副作用还有恶
The most effective drugs for the treatment of congestive heart failure are digitalis glycosides, diuretics and vasodilators. Sympathomimetic drugs such as dopamine and dobutamine may sometimes be used. According to Brounwald’s opinion, digitalis is the most basic drug for the treatment of heart failure and claims that all patients with heart failure, as long as there is no anti-indication, should be applied. However, clinical trials have proved that many defects of digitalis, such as: the positive effect of the drug is not strong role; the maximum effective dose is very close with the poisoning; sick sinus syndrome, atrioventricular block and ventricular arrhythmias Misdiagnosed patients should not be used; the elderly due to slower heart rate, sinus node function is poor, medication should be cautious; In addition, digitalis toxicity, side effects and evil