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目的分析Ⅱ型糖尿病(T2DM)合并社区获得性肺炎(CAP)患者的病原体肺部情况和危险因素。方法选取T2DM合并CAP患者173例定义为T2DM合并CAP组,非糖尿病CAP患者171例定义为非糖尿病CAP组,进行痰液培养分离菌株。结果 173例患者中,121例(占70%)肺部感染症状明显,铜绿假单胞菌72株,构成比最大。多因素Logistic回归分析显示高龄与肺部基础性疾病,是T2DM合并CAP的独立危险因素(高龄:OR=1.744;肺部基础性疾病:OR=2.568)。结论长期稳定控制血糖和肺部基础性疾病对防治T2DM合并CAP患者尤为重要。
Objective To analyze the pathogen lung status and risk factors in type 2 diabetes mellitus (T2DM) patients with community-acquired pneumonia (CAP). Methods Totally 173 T2DM patients with CAP were enrolled in this study. Totally 171 T2DM patients with CAP were enrolled in this study. 171 non-diabetic CAP patients were defined as non-diabetic CAP patients. Results In 173 patients, 121 cases (70%) had obvious pulmonary infection symptoms and 72 strains of Pseudomonas aeruginosa with the largest proportion. Multivariate logistic regression analysis showed that the elderly and pulmonary basic diseases were independent risk factors for T2DM with CAP (OR = 1.744; pulmonary underlying disease: OR = 2.568). Conclusion Long-term and stable control of blood glucose and lung-based diseases is particularly important for the prevention and treatment of T2DM complicated with CAP.