论文部分内容阅读
目的研究明党参Changium smyrnioides根皮的化学成分。方法采用硅胶柱色谱、反相柱色谱以及LH-20凝胶柱色谱等多种技术进行分离纯化,并根据理化性质及波谱数据进行结构鉴定。结果从明党参根皮95%乙醇提取物中分离得到了15个化合物,分别鉴定为欧前胡素(1)、珊瑚菜内酯(2)、花椒毒酚(3)、5-羟基8-甲氧基补骨脂素(4)、香草酸(5)、别欧前胡素(6)、补骨脂素(7)、佛手柑内酯(8)、5-甲氧基-8-O-β-D-葡萄糖基补骨脂素(9)、异茴芹内酯(10)、咖啡酸(11)、橙黄胡椒酰胺乙酸酯(12)、vaginatin(13)、β-谷甾醇(14)、琥珀酸(15)。结论化合物6~13为首次从党参属植物中分离得到。
Objective To study the chemical constituents of root bark of Changium smyrnioides. Methods The compounds were isolated and purified by silica gel column chromatography, reverse phase column chromatography and LH-20 gel column chromatography. Their structures were elucidated on the basis of physico-chemical properties and spectral data. Results Fifteen compounds were isolated from 95% ethanol extract of Radix Codonopsis root, and were identified as Imperatorin (1), Coraline lactone (2), Scutellarin (3), 5- Methoxypsoralen (4), vanillic acid (5), preoplitin (6), psoralen (7), bergapten (8), 5-methoxy- O-β-D-glucosylpsoralen (9), iso anise lactone (10), caffeic acid (11), angostatin (12), vaginatin (13) (14), succinic acid (15). Conclusion Compounds 6-13 are isolated from Codonopsis for the first time.